Summary:

• Published 44 research articles in peer-reviewed journals; 16 articles were published in Nature Photonics, Nature Communications (×2), Optica (×3) and other leading journals as the first author or corresponding author.

• H-index = 26 according to Google Scholar (link).​

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​46. 3D imaging of photoreceptor somas and other subcellular structures in the outer nuclear layer of living healthy and diseased human eyes

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Y. Liu, Q. Ji, M. T. Bernucci, K. Bowles-Johnson, M. J. Keller, J. A. Crowell, K. Kurokawa, D. T. Miller, In preparation.

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45. High-speed adaptive optics reduces temporal noise in functional retinal imaging

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Z. Xu, K. Parkins, D. F. Gutierrez, J. LaPorta; L. Bernstein, R. F. Cooper, Y. Liu,  D. T. Miller, J. E. McGregor, under review in Investigative Ophthalmology & Visual Science (2026).

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​44. Tracking retinal ganglion cell soma loss in glaucoma reveals progression over months and years

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M. Keller, Y. Liu, M. Bernucci, K. Bowles-Johnson, Q. Ji, J. A. Crowell, K. Kurokawa, W. H. Swanson, B. J. King and D. T. Miller, 

Investigative Ophthalmology & Visual Science (2026), in press.

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​43. Cumulative loss of inner retinal neurons in healthy and glaucoma subjects

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K. Kurokawa, J. Crowell, Y. Liu, M. Bernucci, W. H. Swanson, and D. T. Miller, Investigative Ophthalmology & Visual Science 67, 10-10 (2026).

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​42. Structural analysis of cone photoreceptors in AO-OCT enables S-cone identification by a support vector machine classifier

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Q. Ji, M. Bernucci, Y. Liu, J. A. Crowell, D. J. Miller, and D. T. Miller, Biomedical Optics Express 17, 346-364 (2026).

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​41. Rapid axially scanned and de-scanned line-scan confocal microscopy with a tunable acoustic gradient index of refraction lens for high-speed volumetric in vivo imaging

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K. Mac, S. Kim, T. N. Nguyen, C. Hwang, M. Kim, R. Liu, Y. Liu, J. H. Kim, Y. R. Kim, E. Chung, and H.-S. Kwon, Neurophotonics 12, 045013 (2025).

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​40. Integrated fixation and stimulus channel for adaptive optics ophthalmoscopy

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M. Bernucci*, Y. Liu*, Q. Ji, J. A. Crowell, K. Bowles-Johnson, M. J. Keller, and D. T. Miller, Biomedical Optics Express 16, 4796-4820 (2025).

[Video presentation]​​ [Conference paper]

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​39. High-speed single-exposure time-reversed ultrasonically encoded optical focusing into scattering media with off-axis holography

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W. He, J. Luo, Y. Shen, Y. Liu, Z. Wang, D. Wu, J. Liang, Z. Zhang, D. Qi, Y. Yao, L. Deng, H. Ma, B. Zhang, Z. Sun and S. Zhang, 

Optics Express 33, 25106-25120 (2025).

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​38. Ultrafast adaptive optics for imaging the living human eye

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Y. Liu, J. A. Crowell, K. Kurokawa*, M. T. Bernucci*, Q. Ji*, A. Lassoued, H. Jung, M. Keller, M. Marte, and D. T. Miller, 

Nature Communications, 15(1), 10409 (2024).

[Video presentation]​​

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37. Characterizing presumed displaced retinal ganglion cells in the living human retina of healthy and glaucomatous eyes

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M. Marte, K. Kurokawa, H. Jung, Y. Liu, M. T. Bernucci, B. J. King, and D. T. Miller, Investigative Ophthalmology & Visual Science 65, 20-20 (2024). 

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​36. Acoustic-feedback wavefront-adapted photoacoustic microscopy

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Y. Shen*, J. Ma*, C. Hou*, J. Zhao, Y. Liu#, H.-C. Hsu, T. T. W. Wong, B.-O. Guan, S. Zhang, and L. V. Wang#, Optica 11, 214-221 (2024). # denotes corresponding authors.

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​35. Single-exposure ultrasound-modulated optical tomography with a quaternary phase encoded mask

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J. Luo, D. Wu, Y. Liu#, Z. Li, and Y. Shen#, Optics Letters 48, 2857-2860 (2023). # denotes corresponding authors.

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34. Deep learning-enabled volumetric cone photoreceptor segmentation in adaptive optics optical coherence tomography images of normal and diseased eyes

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S. Soltanian-Zadeh, Z. Liu, Y. Liu, A. Lassoued, C. A. Cukras, D. T. Miller, D. X. Hammer, and S. Farsiu, Biomedical Optics Express 14, 815-833 (2023).

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33. High-speed single-exposure time-reversed ultrasonically encoded optical focusing against dynamic scattering

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J. Luo, Y. Liu, D. Wu, X. Xu, L. Shao, Y. Feng, J. Pan, J. Zhao, Y. Shen, and Z. Li, Science Advances 8, eadd9158 (2022).

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32. Cone photoreceptor dysfunction in retinitis pigmentosa revealed by optoretinography

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A. Lassoued, F. Zhang*, K. Kurokawa*, Y. Liu*, M. T. Bernucci*, J. A. Crowell, and D. T. Miller, Proceedings of the National Academy of Sciences (PNAS) 118, e2107444118 (2021).

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31. Quantitative blood flow estimation in vivo by optical speckle image velocimetry

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M. Qureshi, Y. Liu, K. D. Mac, M. Kim, A. M. Safi, and E. Chung, Optica 8, 1092-1101 (2021).

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30. Self-fluence-compensated functional photoacoustic microscopy

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J. Zhu, C. Liu, Y. Liu, J. Chen, Y. Zhang, K. Yao, and L. Wang, IEEE Transactions on Medical Imaging, 40 (12), 3856-3866 (2021).

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29. An open-source, accurate, and iterative calibration method for liquid-crystal-based spatial light modulators

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Y. Shen#, Z. Hu, D. Wu, C. Ma, Y. Liu#, Optics Communications 495, 127108 (2021). # denotes corresponding authors.

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28. Fluorescence imaging through dynamic scattering media with speckle-encoded ultrasound-modulated light correlation

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H. Ruan*, Y. Liu*, J. Xu, Y. Huang, and C. Yang, Nature Photonics 14, 511-516 (2020).

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Media coverage: 1. Caltech News; 2. Nature Photonics News & Views by Prof. Allard P. Mosk, Nature Photonics 14, 466–467 (2020).

[Video presentation]​​

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27. Fighting against fast speckle decorrelation for light focusing inside live tissue by photon frequency shifting

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J. Yang, L. Li, J. Li, Z. Cheng, Y. Liu, and L. V. Wang, ACS Photonics 7, 837-844 (2020).

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26. Investigating ultrasound–light interaction in scattering media

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Y. Huang, M. Cua, J. Brake, Y. Liu, and C. Yang, Journal of Biomedical Optics 25, 025002 (2020).

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25. Imaging through highly scattering human skulls with ultrasound-modulated optical tomography

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Y. Liu*, R. Cao*, J. Xu, H. Ruan, and C. Yang, Optics Letters 45, 2973-2976 (2020).

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Highlighted in OSA Spotlight on Optics by Prof. Emmanuel Bossy.

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24. Focusing light inside live tissue using reversibly switchable bacterial phytochrome as a genetically encoded photochromic guide star

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J. Yang*, L. Li*, A. A. Shemetov*, S. Lee, Y. Zhao, Y. Liu, Y. Shen, J. Li, Y. Oka, V. V. Verkhusha, and L. V. Wang, Science Advances 5, eaay1211 (2019).

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23. Wavefront shaping with disorder-engineered metasurfaces

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M. Jang*, Y. Horie*, A. Shibukawa*, J. Brake, Y. Liu, S. M. Kamali, A. Arbabi, H. Ruan, A. Faraon, and C. Yang, Nature Photonics 

12(2), 84-90 (2018).

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22. Time-reversed ultrasonically encoded optical focusing through highly scattering ex vivo human cataractous lenses

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Y. Liu*, Y. Shen*, H. Ruan, F. Brodie, T. T. W. Wong, C. Yang, and L. V. Wang, Journal of Biomedical Optics 23(1), 010501 (2018).

[Video presentation]​​

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21. Deep-tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light

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H. Ruan*, J. Brake*, J. Robinson, Y. Liu, M. Jang, C. Xiao, C. Zhou, V. Gradinaru, and C. Yang, Science Advances 3(12), (2017).

[Poster presentation]​​​

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20. High-speed single-shot optical focusing through dynamic scattering media with full-phase wavefront shaping

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A. S. Hemphill, Y. Shen, Y. Liu, and L. V. Wang, Applied Physics Letters 111(22), 221109 (2017).

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19. Focusing light inside dynamic scattering media with millisecond digital optical phase conjugation

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Y. Liu, C. Ma, Y. Shen, J. Shi and L. V. Wang,  Optica  4(2), 280-288 (2017).

[Video presentation]​​

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18. Focusing light through scattering media by polarization modulation based generalized digital optical phase conjugation

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J. Yang*, Y. Shen*, Y. Liu, A. S. Hemphill, and L. V. Wang, Applied Physics Letters 111(20),201108 (2017).

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17. Focusing light inside scattering media with magnetic-particle-guided wavefront shaping

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H. Ruan, T. Haber, Y. Liu, J. Brake, J. Kim, J. M. Berlin and C. Yang,  Optica  4(11), 1337-1343 (2017).

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​16. Sub-Nyquist sampling boosts targeted light transport through opaque scattering media

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Y. Shen*, Y. Liu*, C. Ma, and L. V. Wang,  Optica  4, 97-102 (2017).

[Poster presentation]​​

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15. In vivo study of optical speckle decorrelation time across depths in the mouse brain

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M. M. Qureshi*, J. Brake*, H. J. Jeon, H. Ruan, Y. Liu, A. M. Safi, T. J. Eom, C. Yang and E. Chung, Biomedical Optics Express

8(11), 4855-4864 (2017).

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14. Focusing light through scattering media by transmission matrix inversion

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J. Xu, H. Ruan, Y. Liu, H. Zhou and C. Yang, Optics Express 25(22), 27234-27246 (2017).

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13. Lock-in camera based heterodyne holography for ultrasound-modulated optical tomography inside dynamic scattering media

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Y. Liu, Y. Shen, C. Ma, J. Shi, and L. V. Wang, Applied Physics Letters 108, 231106 (2016).

[Video presentation]​​

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12. Focusing light through biological tissue and tissue-mimicking phantoms up to 9.6 centimeters in thickness with digital optical phase conjugation

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Y. Shen*, Y. Liu*, C. Ma, and L. V. Wang, Journal of Biomedical Optics 21(8), 085001 (2016).

[Poster presentation]​​

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11. Bit-efficient, sub-millisecond wavefront measurement using a lock-in camera for time-reversal based optical focusing inside scattering media

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Y. Liu, C. Ma, Y. Shen, and L. V. Wang, Optics Letters 41, 1321-1324 (2016).

[Video presentation]​​

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10. Focusing light through scattering media by full-polarization digital optical phase conjugation

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Y. Shen*, Y. Liu*, C. Ma, and L. V. Wang, Optics Letters 41, 1130-1133 (2016).

[Video presentation]​​

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9. Single-exposure optical focusing inside scattering media using binarized time-reversed adapted perturbation

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C. Ma*, F. Zhou*, Y. Liu, and L. V. Wang,  Optica  2, 869-876 (2015).

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8. Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light

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Y. Liu*, P. Lai*, C. Ma, X. Xu, A. Grabar, and L. V. Wang, Nature Communications 6, 5904 (2015).

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Reported in Nature, “Optics: Super vision”, Nature, 518(7538):158-160 (2015).

[Video presentation]​​  [Poster presentation]​​

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7. Photobleaching imprinting microscopy: seeing clearer and deeper

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L. Gao, A. Garcia, Y. Liu, C. Li, and L. V. Wang,  Journal of Cell Science  127(2), 288-294 (2014).

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6. Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media

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C. Ma, X. Xu, Y. Liu, and L. V. Wang, Nature Photonics 8(12), 931-936 (2014).

[Poster presentation]​​

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5. Optical sectioning by wide-field photobleaching imprinting microscopy

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C. Li*, L. Gao*, Y. Liu, and L. V. Wang,  Applied Physics Letters  103(18) (2013).

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4. Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals

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J. Xia, A. Danielli, Y. Liu, L. Wang, K. Maslov, and L. V. Wang, Optics Letters 38(15), 2800-2803 (2013).

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3. Single-cell photoacoustic thermometry

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L. Gao, L. Wang, C. Li, Y. Liu, H. Ke, C. Zhang, and L. V. Wang, Journal of Biomedical Optics 18(2), 026003 (2013).

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2. Quantitative evaluation of scattering in optical coherence tomography skin images using the extended Huygens-Fresnel theorem

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M. R. N. Avanaki, A. G. Podoleanu, J. B. Schofield, C. Jones, M. Sira, Y. Liu, and A. Hojjat, Applied Optics 52(8), 1574-1580 (2013).

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1. Effects of light scattering on optical-resolution photoacoustic microscopy

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Y. Liu, C. Zhang, and L. V. Wang,  Journal of Biomedical Optics  17(12), 126014 (2012).

[Poster presentation]​​​

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Selected conference publications

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1. An integrated fixation and stimulus channel for adaptive optics ophthalmoscopy with a large working distance, steering field, dioptric range, and light efficiency

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Y. Liu*, M. Bernucci*, Q. Ji, J. Crowell, K. Bowles-Johnson, M. Keller, and D. Miller, Proceedings of SPIE 12824, Ophthalmic Technologies XXXIV, 1282402 (2024).

[Video presentation]​​ [Conference paper pdf]

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